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Hi, I'm Tuyen πŸ‘‹

Pediatric surgeon by training. Meta-researcher by conviction.

I study how AI changes the way we do science β€” not just faster, but structurally differently. My work sits at the intersection of clinical research, AI systems, and philosophy of science.

πŸ”¬ What I'm working on

The problem I named: When AI assists research, it introduces epistemic drift β€” a silent corruption of the reasoning chain that leaves no trace in final results. Peer review can't catch it. Reproducibility checks miss it. Current safeguards assume human-controlled reasoning. AI breaks that assumption.

The other problem I'm working on: Evidence hierarchies built around RCTs misfire on operator-dependent medicine (surgery, IR, endoscopy, anaesthesia). I'm building OPERA β€” a constraint-driven appraisal rubric that scores trials on what they actually controlled for, not what design label they wore.

What I'm building:

Project What it does
epistemic-drift Taxonomy of how AI corrupts scientific reasoning β€” companion to the A-series papers
citecheck Verify manuscript citations against PubMed, CrossRef, OpenAlex β€” trust but verify
sr-pipeline End-to-end systematic review automation: dedup + AI screening + PRISMA β€” 68 tests βœ“

πŸ“ Writing

I write about medical research and how to integrate AI in academic works at https://www.tuyentranmd.com/.

Core belief: AI assists thinking. You own the science.

🧭 Research direction

  • Accepted: Neonatal Anorectal Malformations β€” Journal of Pediatric Surgery (in press)
  • Under review: "Artificial Intelligence and the Epistemic Drift of Scientific Research" β€” defining a new class of epistemic failure in AI-assisted research
  • In flight: OPERA framework β€” conceptual paper + empirical companion
  • In flight: Constitutional framework for AI in science β€” why research needs pre-commitment constraints, not just post-hoc guidelines

πŸ“« Reach me

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"The crisis is not that AI makes bad science β€” it's that AI makes science that looks indistinguishable from good science."

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