Thymic NK-cell development — single-cell mtDNA clonal lineage tracing (mgatk/ReDeeM), clone inference and HPC pipelines

Analysis code for a study of NK-cell plasticity and CD160 in the tumour microenvironment (bulk + single-cell RNA-seq, gene-network analysis)

Re-analysis of the Tang et al. 2023 (Cell) pan-cancer NK-cell atlas with CD160/DGAT signature scoring

Re-analysis of the McFarland et al. 2021 (Cell Reports) multi-tissue mouse NK/ILC1 scRNA-seq dataset

Re-analysis of the Crinier et al. 2020 human bone-marrow NK-cell differentiation scRNA-seq dataset

Re-analysis of the Bai et al. 2021 (Science) mouse liver ILC1 dataset, integrated with in-house NK data

Re-analysis of the Crinier et al. 2018 (Immunity) human & mouse NK-cell scRNA-seq datasets

Re-analysis of the Hao et al. 2021 (Cell) multimodal CITE-seq PBMC reference (NKG7 / DNAM focus)

Re-analysis of the Borcherding et al. 2024 (Nature Immunology) pan-cancer tumour-infiltrating NK-cell reference

Analysis of the Kramer et al. human liver ILC1 (type-1 innate lymphoid cell) single-cell dataset

In-silico structural & evolutionary characterisation of NKG7 (cytotoxic-lymphocyte granule tetraspan): structure prediction + homology + pore analysis. Tests the ion-channel hypothesis — finds a self-associating claudin/Ca_V-γ scaffold, not a pore.

Re-analysis of the Dean et al. 2024 (Nat Commun) Kaede NK-cell tumour-entry dataset with a CD160 signature overlay