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COVID-19 Economy-Mortality Nexus Analysis Pipeline

Overview

Modular R pipeline analyzing relationships between economic development, healthcare systems, demographics, and COVID-19 mortality outcomes. Implements GAM-based temporal standardization for robust cross-country comparisons.

Pipeline Structure

├── README.md
├── 00_library_loader.R          # Package management & helper functions
├── 01_loader.R                  # Raw data loading & ISO standardization  
├── 02_clean.R                   # GAM mortality estimation & integration
├── 03_analysis.R                # Correlation analysis & complete cases
├── 04a_plots_correlations.R     # Figure 3: Correlation heatmap
├── 04b_plots_maps.R             # Figure 2: Coverage map
├── 04c_tables.R                 # Tables 1-4: Subgroups, interactions, GDP thresholds
├── 04d_partial_correlations.R   # Section 3.2: Suppression effects
├── 04e_plots_maps_quartile.R    # Quartile distribution maps for all variables
├── DATA_SOURCES.md
├── data_raw/                    # Original datasets
├── data_manipulated/            # Processed data
└── outputs/                     # Final figures, tables, results

Data Sources

See DATA_SOURCES.md for complete licensing information and snapshot dates.

Datasets include:

  • Median age (UN WPP 2024 via OWID)
  • Population ages 65+ (World Bank WDI via UN WPP)
  • GDP per capita, PPP (World Bank WDI, 2017 base year)
  • UHC service coverage (WHO via World Bank)
  • Cumulative excess mortality (HMD/WMD via OWID)
  • Cumulative COVID-19 vaccination doses (OWID/WHO)

Key Methodological Improvements

Dual Age Indicators:

  • Median age (years): General population age structure
  • Population 65+ (%): Direct measure of high-risk demographic
  • Enables robustness checks across different age operationalizations
  • Both based on 2022 data (median age: UN WPP; 65+: World Bank WDI)

Vaccination Data:

  • Uses nearest_date() approach: closest observation to 2023-05-05 (WHO/OWID standard)
  • Ensures temporal consistency across countries
  • Cumulative doses per 100 people

GAM Mortality Estimation:

  • Robust error handling with try() prevents pipeline crashes
  • Dynamic k parameter prevents mgcv errors on short time series
  • Index-free date prediction eliminates off-by-one errors
  • Fallback for dates outside observation range

ISO3 Standardization:

  • Systematic map_iso3() function with manual overrides
  • Handles Kosovo, Micronesia, Virgin Islands, Saint Martin
  • Prevents country loss due to name matching failures

Analysis Outputs

Tables:

  • Table 1: Subgroup correlations (median age splits)
  • Table 2: Subgroup correlations (age 65+ splits)
  • Table 3: OLS interaction models (age × UHC, age × vaccination)
  • Table 4: GDP threshold analysis

Figures:

  • Correlation heatmaps (Pearson & Spearman)
  • Coverage maps showing data availability
  • Quartile distribution maps for all 6 variables

Quick Start

# Run complete pipeline:
source("01_loader.R")
source("02_clean.R") 
source("03_analysis.R")
source("04a_plots_correlations.R")
source("04b_plots_maps.R")
source("04c_tables.R")
source("04d_partial_correlations.R")
source("04e_plots_maps_quartile.R")s

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