Skip to content
View alexmaropakis's full-sized avatar
😁
Focusing
😁
Focusing

Block or report alexmaropakis

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please don’t include any personal information such as legal names or email addresses. Markdown is supported. This note will only be visible to you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
alexmaropakis/README.md

Who am I?

I am a M.S. in Cell and Gene Therapies candidate at Northeastern University with a B.S. in Behavioral Neuroscience. I am currently conducting research in the fields of systems and computational proteomics-based neuroscience in the Sabatini Lab at Harvard Medical School, and Slavov Lab at Northeastern University, respectively.

Research

  • My work at the Slavov Lab aims to understand the role of alternative RNA decoding in neurodegeneration and aging, using a mass spectrometry proteomics-based approach.
  • My work at the Sabatini Lab aims to study how dopaminergic modulation of striatal circuits is involved in learning, motivation, and movement using closed-loop in vivo optogenetics.

Projects

Mass Spectrometry Proteomics

  • BrainDecode - a pipeline for investigating the role of substituted amino acid peptides in aging and neurodegeneration using mass spectrometry proteomics datasets.
  • MaxQuant in Linux Tutorial - an updated tutorial for using the quantitative proteomics search engine MaxQuant in Linux environments.
  • FragPipe in Linux Pipeline for the AAS Project (WIP) - a pipeline for using the quantitative proteomics search engine FragPipe in Linux environments, particularly for the AAS project (ref. BrainDecode) but also generalizable for database searches using FASTAs without custom peptide appended.

Behavioral Analysis Pipelines

  • PraxisDAP (WIP) - a data analysis pipeline for data produced from closed-loop, optogenetic licking and lever pressing tasks.

Other

  • ObscuraApp - an unofficial app for storing character and circle sheets for the tabletop roleplaying game Candela Obscura, developed by Critical Role's publishing company Darrington Press.

Pinned Loading

  1. BrainDecode BrainDecode Public

    Pipeline for AAS analysis of aging and neurodegeneration proteomics datasets.

    Jupyter Notebook

  2. MaxQuant_Linux_Tutorial MaxQuant_Linux_Tutorial Public

    An updated guide for running MaxQuant in Linux.

    Python

  3. FragPipe_Linux_Pipeline_AAS FragPipe_Linux_Pipeline_AAS Public

    An pipeline for running FragPipe in Linux (heavy on the amino acid substitution project).

    Python