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feat: 3 ADHD + 2 MAOI drug cards (batch 7, completes daily-practice arsenal) - #16

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Apr 25, 2026
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feat: 3 ADHD + 2 MAOI drug cards (batch 7, completes daily-practice arsenal)#16
BenBakster merged 1 commit into
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feat/drug-cards-adhd-maoi

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Final batch closing the ADHD adult/child + MAOI gaps. After this drug card portfolio covers the full daily-practice psychiatric arsenal.

ADHD (3, category Нейроразвитие):
- drug_methylphenidate (Ritalin/Concerta) — NDRI, 1st-line for child ADHD
  per Cortese 2018 NM-A, 4 forms (IR/SR/OROS/patch), Schedule II
- drug_atomoxetine (Strattera) — NRI, FIRST non-stimulant approved (2002),
  no abuse potential, 24h coverage, ⚠ slow onset 4-8 wk, CYP2D6 PM watch
- drug_lisdexamfetamine (Vyvanse) — pro-drug d-amphetamine cleaved by RBC
  enzymes, smoothed PK, abuse-resistant design, FDA ADHD + BED (only
  stimulant for binge eating)

MAOI (2, category Фармакотерапия (АД)):
- drug_phenelzine (Nardil) — hydrazine non-selective irreversible MAOI,
  ⭐ best for ATYPICAL depression (Quitkin 1990), ⚠ tyramine diet + 2-week
  washout to/from any serotonergic drug
- drug_tranylcypromine (Parnate) — cyclopropylamine MAOI, amphetamine-like,
  ACTIVATING profile (vs sedating phenelzine), faster onset (1 wk),
  preferred for retarded/anhedonic depression

Stats: 169 → 174 entries (+5), 699 → 729 citations.

🎯 Drug card portfolio now ~complete for daily Ukrainian psychiatric practice:
- 19 antipsychotics (FGAs + SGAs incl. Ukrainian formulary)
- 21 antidepressants (5 SSRI + 4 atypical + 2 SNRI + 4 TCA + 2 MAOI + 4 reference entries)
- 9 anxiolytics + 7 hypnotics
- 9 mood stabilizers + 4 ADHD agents
- 16 narcology entries (incl 4 anti-craving drugs cards)
@BenBakster
BenBakster merged commit a5d62b8 into main Apr 25, 2026
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