This is essentially a variant of the splitting of the spectra into the shared (matched) and unique (non-matched) spectra in two-sample comparisons. Applied to N-vs-N comparison, it would be useful to remove all spectra from both datasets being compared that also match spectra in a third dataset (representing experimental background, a negative control, known contaminants, or similar). But the option should be made available in the N-vs-N comparison, e.g. allow the user to add a third dataset of spectra to be removed before comparison.
This should be an advanced option.
This is essentially a variant of the splitting of the spectra into the shared (matched) and unique (non-matched) spectra in two-sample comparisons. Applied to N-vs-N comparison, it would be useful to remove all spectra from both datasets being compared that also match spectra in a third dataset (representing experimental background, a negative control, known contaminants, or similar). But the option should be made available in the N-vs-N comparison, e.g. allow the user to add a third dataset of spectra to be removed before comparison.
This should be an advanced option.