diff --git a/src/hatch/cli/application.py b/src/hatch/cli/application.py
index 1fef37d16..134e865d9 100644
--- a/src/hatch/cli/application.py
+++ b/src/hatch/cli/application.py
@@ -159,6 +159,8 @@ def ensure_plugin_dependencies(self, dependencies: list[Dependency], *, wait_mes
         if not dependencies:
             return
 
+        from uv import find_uv_bin
+
         from hatch.dep.sync import InstalledDistributions
         from hatch.env.utils import add_verbosity_flag
 
@@ -178,9 +180,10 @@ def ensure_plugin_dependencies(self, dependencies: list[Dependency], *, wait_mes
             if distributions.dependencies_in_sync(dependencies):
                 return
 
-            pip_command = [sys.executable, "-u", "-m", "pip"]
+            uv_bin = find_uv_bin()
+            pip_command = [uv_bin, "pip"]
 
-        pip_command.extend(["install", "--disable-pip-version-check"])
+        pip_command.extend(["install", "--disable-pip-version-check", "--python", sys.executable])
 
         # Default to -1 verbosity
         add_verbosity_flag(pip_command, self.verbosity, adjustment=-1)
diff --git a/tests/conftest.py b/tests/conftest.py
index 7b38a299e..df74d00ad 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -481,15 +481,25 @@ def mock_process(command, **kwargs):
 
 @pytest.fixture
 def mock_plugin_installation(mocker):
+    from uv import find_uv_bin
+
     subprocess_run = subprocess.run
     mocked_subprocess_run = mocker.MagicMock(returncode=0)
 
     def _mock(command, **kwargs):
         if isinstance(command, list):
+            if any(arg.startswith("hatchling") for arg in command):
+                return subprocess_run(command, **kwargs)
+
             if command[:5] == [sys.executable, "-u", "-m", "pip", "install"]:
                 mocked_subprocess_run(command, **kwargs)
                 return mocked_subprocess_run
 
+            uv_bin = find_uv_bin()
+            if command[:3] == [uv_bin, "pip", "install"]:
+                mocked_subprocess_run(command, **kwargs)
+                return mocked_subprocess_run
+
             if command[:3] == [sys.executable, "self", "python-path"]:
                 return mocker.MagicMock(returncode=0, stdout=sys.executable.encode())
 
diff --git a/tests/helpers/helpers.py b/tests/helpers/helpers.py
index 52b9fdffd..570fc1c53 100644
--- a/tests/helpers/helpers.py
+++ b/tests/helpers/helpers.py
@@ -48,13 +48,16 @@ def get_current_timestamp():
 
 
 def assert_plugin_installation(subprocess_run, dependencies: list[str], *, verbosity=0, count=1):
+    from uv import find_uv_bin
+
+    uv_bin = find_uv_bin()
     command = [
-        sys.executable,
-        "-u",
-        "-m",
+        uv_bin,
         "pip",
         "install",
         "--disable-pip-version-check",
+        "--python",
+        sys.executable,
     ]
     add_verbosity_flag(command, verbosity, adjustment=-1)
     command.extend(dependencies)