diff --git a/src/app/core/substance-details/substance-cards-filters.constant.ts b/src/app/core/substance-details/substance-cards-filters.constant.ts
index fa8b771a3..fb96697b1 100644
--- a/src/app/core/substance-details/substance-cards-filters.constant.ts
+++ b/src/app/core/substance-details/substance-cards-filters.constant.ts
@@ -42,6 +42,10 @@ export const substanceCardsFilters: Array<SubstanceCardFilter> = [
     {
         name: 'isInGroups',
         filter: groupFilter
+    },
+    {
+         name: "showDependenciesFilter",
+         filter: showDependenciesFilter
     }
 ];
 
@@ -213,6 +217,41 @@ export function substanceRelationshipsFilter(
     });
 }
 
+export function showDependenciesFilter(
+    substance: SubstanceDetail,
+    filter: SubstanceCardFilterParameters
+): Observable<boolean> {
+    const requiredCodeSystem = "POWO";
+    const requiredClass = "structurallyDiverse";
+    const requiredReferenceType = "IMAGE REFERENCE";
+
+    return new Observable(observer => {
+
+        let showDependencies = false;
+
+        if (substance.codes && substance.codes.length > 0 && substance.substanceClass ===  requiredClass) {
+
+            for (let i = 0; i < substance.codes.length; i++) {
+                if(requiredCodeSystem === substance.codes[i].codeSystem && 
+                    substance.codes[i].url && substance.codes[i].url.length > 0) {
+                        showDependencies = true;
+                    }
+                } 
+        }
+        if( !showDependencies && substance.references && substance.references.length >0) {
+            for (let i = 0; i < substance.references.length; i++) {
+                if( substance.references[i].docType === requiredReferenceType 
+                    && substance.references[i].uploadedFile
+                    && substance.references[i].uploadedFile.length > 0 ) {
+                        showDependencies = true;
+                }
+            }
+        }
+        observer.next(showDependencies);
+        observer.complete();
+    });
+}
+
   export function credentialsFilter(
     substance: SubstanceDetail,
     filter: SubstanceCardFilterParameters,
diff --git a/src/app/fda/config/config.json b/src/app/fda/config/config.json
index 28c36488a..a1c897428 100644
--- a/src/app/fda/config/config.json
+++ b/src/app/fda/config/config.json
@@ -134,14 +134,7 @@
       "title": "Substance Dependencies",
       "filters": [
         {
-          "filterName": "exists",
-          "propertyToCheck": "references"
-        },
-        {
-          "filterName": "equals_in_array",
-          "propertyToCheck": "references",
-          "value": "IMAGE REFERENCE",
-          "propertyInArray": "docType"
+          "filterName": "showDependenciesFilter"
         }
       ]
     },