diff --git a/setup.py b/setup.py
index 9ed8574..d90dc4e 100644
--- a/setup.py
+++ b/setup.py
@@ -34,7 +34,7 @@ def get_version():
       tests_require=['nose'],
       install_requires=['pathlib2==2.3.7',
                         'preconditions==0.1',
-                        'numpy==1.19.5',
+                        'numpy==1.22.0',
                         'pandas==1.1.5',
                         'pysam==0.19.0',
                         'plastid==0.6.1',