Data below the limit of quantification (or BLQ) could be handled using a likelihood based censoring method [1].
BLQ can be specified using the CENS column supported by rxode2 [2].
[1] Beal 2001, https://doi.org/10.1023/A:1012299115260
[2] https://nlmixr2.github.io/rxode2/articles/rxode2-datasets.html?q=censored#censlimit-columns
Data below the limit of quantification (or BLQ) could be handled using a likelihood based censoring method [1].
BLQ can be specified using the CENS column supported by
rxode2[2].[1] Beal 2001, https://doi.org/10.1023/A:1012299115260
[2] https://nlmixr2.github.io/rxode2/articles/rxode2-datasets.html?q=censored#censlimit-columns