Appropriately validated popPK models based on real-world data are lacking

[levenc]

Issue:

• The literature is abundant in population pharmacokinetic (popPK) models, but models suitable for individual dosage adjustment are rare.
• Quality and generalizability criteria need to be established in order to collectively select models that are potentially useful at the patient's bedside.

Suggested solution:

• The Therapeutic Drug Monitoring - Customisation of Treatments group of the Société Française de Pharmacologie et de Thérapeutique (French Society of Pharmacology and Therapeutics) has begun this work.
• The models resulting from this collective work should be included by default in posologyr.