Hello,
I decided to check an reproducibility of results HLA-typing by xHLA. I run xHLA on one sample 10 times and , unfortunately, I got different results. I can suggest that this is due to some difficult regions for alignment (e.g. HLA-B*44:138Q: Evidence for a Confined Deletion and Recombination Events in an Otherwise Unaffected HLA-haplotype). But I can't understand which result is correct and which result isn't. For illustration this case I attach output files for 2 samples with 2 different results.
Can you explain why I get different results?
Thanks,
Polina.
Hello,
I decided to check an reproducibility of results HLA-typing by xHLA. I run xHLA on one sample 10 times and , unfortunately, I got different results. I can suggest that this is due to some difficult regions for alignment (e.g. HLA-B*44:138Q: Evidence for a Confined Deletion and Recombination Events in an Otherwise Unaffected HLA-haplotype). But I can't understand which result is correct and which result isn't. For illustration this case I attach output files for 2 samples with 2 different results.
Can you explain why I get different results?
Thanks,
Polina.