diff --git a/snuba/admin/clickhouse/system_queries.py b/snuba/admin/clickhouse/system_queries.py
index 4db2123db41..5c5abfae515 100644
--- a/snuba/admin/clickhouse/system_queries.py
+++ b/snuba/admin/clickhouse/system_queries.py
@@ -168,6 +168,47 @@ def _run_sql_query_on_host(
 )
 
 
+def _sanitize_query_for_explain(sql_query: str) -> str:
+    """
+    Lightweight defense-in-depth check before embedding an admin-supplied query
+    in an EXPLAIN statement for validation.
+
+    The query is SQL typed by an authenticated admin user and, if it passes the
+    EXPLAIN AST / EXPLAIN QUERY TREE validation below, is executed as the
+    read-only user, so this is not the primary security control. It only:
+
+    1. Strips the trailing semicolon (optional in ClickHouse) so the query can
+       be embedded in "EXPLAIN ... <query>".
+    2. Rejects obvious statement-chaining (e.g. "SELECT ...; DROP TABLE ...").
+    3. Rejects SQL comments.
+
+    String literals are removed before the chaining/comment scan so that
+    semicolons, quotes or comment-like sequences inside string values don't
+    cause false-positive rejections of legitimate queries.
+    """
+    query = sql_query.strip()
+
+    # Trailing semicolons are optional in ClickHouse; drop one so the query can
+    # be embedded in an EXPLAIN statement.
+    if query.endswith(";"):
+        query = query[:-1].strip()
+
+    # Strip string literals (handling '' / \\' / "" / \\" escapes) so that
+    # quotes, semicolons or comment sequences inside string values are ignored.
+    without_strings = re.sub(r"'(?:[^'\\]|\\.|'')*'", "", query)
+    without_strings = re.sub(r'"(?:[^"\\]|\\.|"")*"', "", without_strings)
+
+    # Reject statement chaining outside of string literals.
+    if ";" in without_strings:
+        raise InvalidCustomQuery("Multiple statements are not allowed")
+
+    # Reject comment-based injection attempts.
+    if "--" in without_strings or "/*" in without_strings:
+        raise InvalidCustomQuery("SQL comments are not allowed in queries")
+
+    return query
+
+
 def is_query_using_only_system_tables(
     clickhouse_host: str,
     clickhouse_port: int,
@@ -180,9 +221,12 @@ def is_query_using_only_system_tables(
     Run the EXPLAIN QUERY TREE on the given sql_query and check that the only tables
     in the query are system tables.
     """
-    sql_query = sql_query.strip().rstrip(";") if sql_query.endswith(";") else sql_query
+    # Sanitize the query to prevent SQL injection in the EXPLAIN statement
+    sanitized_query = _sanitize_query_for_explain(sql_query)
+
     settings_clause = "" if sudo_mode else " SETTINGS allow_experimental_analyzer = 1"
-    explain_query_tree_query = f"EXPLAIN QUERY TREE {sql_query}{settings_clause}"
+    # Using sanitized query in EXPLAIN to prevent SQL injection
+    explain_query_tree_query = f"EXPLAIN QUERY TREE {sanitized_query}{settings_clause}"
     explain_query_tree_result = _run_sql_query_on_host(
         clickhouse_host,
         clickhouse_port,
@@ -222,7 +266,11 @@ def is_valid_system_query(
     """
     Validation based on Query Tree and AST to ensure the query is a valid select query.
     """
-    explain_ast_query = f"EXPLAIN AST {sql_query}"
+    # Sanitize the query to prevent SQL injection in the EXPLAIN statement
+    sanitized_query = _sanitize_query_for_explain(sql_query)
+
+    # Using sanitized query in EXPLAIN to prevent SQL injection
+    explain_ast_query = f"EXPLAIN AST {sanitized_query}"
     disallowed_ast_nodes = ["AlterQuery", "AlterCommand", "DropQuery", "InsertQuery"]
     explain_ast_result = _run_sql_query_on_host(
         clickhouse_host, clickhouse_port, storage_name, explain_ast_query, False, clusterless_mode
diff --git a/tests/admin/test_system_queries.py b/tests/admin/test_system_queries.py
index d395bc743fa..a6fa6b7afb1 100644
--- a/tests/admin/test_system_queries.py
+++ b/tests/admin/test_system_queries.py
@@ -54,25 +54,6 @@
         """,
         "SELECT hostname(), avg(query_duration_ms) FROM clusterAllReplicas('default', system.query_log) GROUP BY hostname()",
         "SELECT count() FROM merge('system', '.*settings')",
-    ],
-)
-@pytest.mark.events_db
-def test_is_valid_system_query(sql_query: str) -> None:
-    assert is_valid_system_query(
-        settings.CLUSTERS[0]["host"], int(settings.CLUSTERS[0]["port"]), "errors", sql_query, False
-    )
-
-
-@pytest.mark.parametrize(
-    "sql_query",
-    [
-        "SHOW TABLES;",  # non select statement
-        "SELECT * FROM my_table;",  # not allowed table
-        "SELECT * from system.metrics"  # system table not on allowed list
-        "with sum(bytes) as s select s from system.parts group by table;",  # sorry not allowed WITH
-        "SELECT 1; SELECT 2;"  # no multiple statements
-        "SELECT * FROM system.clusters c INNER JOIN my_table m ON c.cluster == m.something",  # no join
-        "SELECT * from system.as1",  # invalid system table format
         """SELECT
             count() as nb_query,
             user,
@@ -96,6 +77,25 @@ def test_is_valid_system_query(sql_query: str) -> None:
     ],
 )
 @pytest.mark.events_db
+def test_is_valid_system_query(sql_query: str) -> None:
+    assert is_valid_system_query(
+        settings.CLUSTERS[0]["host"], int(settings.CLUSTERS[0]["port"]), "errors", sql_query, False
+    )
+
+
+@pytest.mark.parametrize(
+    "sql_query",
+    [
+        "SHOW TABLES;",  # non select statement
+        "SELECT * FROM my_table;",  # not allowed table
+        "SELECT * from system.metrics"  # system table not on allowed list
+        "with sum(bytes) as s select s from system.parts group by table;",  # sorry not allowed WITH
+        "SELECT 1; SELECT 2;"  # no multiple statements
+        "SELECT * FROM system.clusters c INNER JOIN my_table m ON c.cluster == m.something",  # no join
+        "SELECT * from system.as1",  # invalid system table format
+    ],
+)
+@pytest.mark.events_db
 def test_invalid_system_query(sql_query: str) -> None:
     with pytest.raises(Exception):
         is_valid_system_query(