Hi,
I'm glad to have learned this method, but I'm still a bit confused.
How to interpret the obtained cluster results and figures?
How can I determine which SNPs are heterogeneous and need to be excluded?
In the figures, there are SNPs with positive and negative effects. Are the results between them conflicting?
Should I only retain SNPs whose beta values are in the same direction as the two-sample MR results
Thanks much!

Hi,
I'm glad to have learned this method, but I'm still a bit confused.
How to interpret the obtained cluster results and figures?
How can I determine which SNPs are heterogeneous and need to be excluded?
In the figures, there are SNPs with positive and negative effects. Are the results between them conflicting?
Should I only retain SNPs whose beta values are in the same direction as the two-sample MR results
Thanks much!