Hello,
Thanks for developing such an efficient tool to perform multi-trait colocalization. When i am using the tool recently, I notice in one locus that the "candidate_snp" is different from the lead SNP from my data set. this candidate SNP, however, has a very small and different "posterior_explained_by_snp" probability than from the output. the lead SNP is the one that has the max posterior_explained_by_snp. This hasn't happen to me before or other loci. I'm curious if anyone else observed the same and wanted to flag.
Best,
KD
Hello,
Thanks for developing such an efficient tool to perform multi-trait colocalization. When i am using the tool recently, I notice in one locus that the "candidate_snp" is different from the lead SNP from my data set. this candidate SNP, however, has a very small and different "posterior_explained_by_snp" probability than from the output. the lead SNP is the one that has the max posterior_explained_by_snp. This hasn't happen to me before or other loci. I'm curious if anyone else observed the same and wanted to flag.
Best,
KD