diff --git a/agentteams-controller/internal/initializer/initializer.go b/agentteams-controller/internal/initializer/initializer.go
index c4fbd9dee..0ab0aea6a 100644
--- a/agentteams-controller/internal/initializer/initializer.go
+++ b/agentteams-controller/internal/initializer/initializer.go
@@ -362,7 +362,7 @@ func (i *Initializer) initGatewayRoutes(ctx context.Context) error {
 					time.Sleep(2 * time.Second)
 					raw := map[string]interface{}{
 						"hiclawMode":              true,
-						"openaiCustomUrl":         cfg.OpenAIBaseURL,
+						"openaiCustomUrl":         customOpenAIURL(cfg.OpenAIBaseURL),
 						"openaiCustomServiceName": "openai-compat.dns",
 						"openaiCustomServicePort": port,
 					}
@@ -396,7 +396,7 @@ func (i *Initializer) initGatewayRoutes(ctx context.Context) error {
 					time.Sleep(2 * time.Second)
 					raw := map[string]interface{}{
 						"hiclawMode":              true,
-						"openaiCustomUrl":         cfg.OpenAIBaseURL,
+						"openaiCustomUrl":         customOpenAIURL(cfg.OpenAIBaseURL),
 						"openaiCustomServiceName": provider + ".dns",
 						"openaiCustomServicePort": port,
 					}
@@ -448,6 +448,25 @@ func (i *Initializer) initGatewayRoutes(ctx context.Context) error {
 	return nil
 }
 
+// customOpenAIURL returns the base URL with any port stripped while preserving
+// everything else (escaped path, query string, fragment). Higress derives the
+// upstream host domain from openaiCustomUrl, so an embedded port would be
+// treated as part of the host and break DNS resolution. The port is supplied
+// separately via openaiCustomServicePort.
+func customOpenAIURL(rawURL string) string {
+	u, err := url.Parse(rawURL)
+	if err != nil || u.Hostname() == "" {
+		return rawURL
+	}
+	host := u.Hostname()
+	if strings.Contains(host, ":") {
+		// Re-bracket IPv6 literals so the reconstructed URL stays valid.
+		host = "[" + host + "]"
+	}
+	u.Host = host
+	return u.String()
+}
+
 // parseHostPort extracts host and port from a URL like "http://host:port".
 func parseHostPort(rawURL string) (string, int, error) {
 	u, err := url.Parse(rawURL)
diff --git a/agentteams-controller/internal/initializer/initializer_test.go b/agentteams-controller/internal/initializer/initializer_test.go
new file mode 100644
index 000000000..7e7b9fee4
--- /dev/null
+++ b/agentteams-controller/internal/initializer/initializer_test.go
@@ -0,0 +1,28 @@
+package initializer
+
+import "testing"
+
+func TestCustomOpenAIURL(t *testing.T) {
+	cases := []struct {
+		name string
+		in   string
+		want string
+	}{
+		{"ip port with path", "http://10.43.46.12:3000/v1", "http://10.43.46.12/v1"},
+		{"ip port no path", "http://10.43.46.12:3000", "http://10.43.46.12"},
+		{"https port with path", "https://example.com:8443/v1", "https://example.com/v1"},
+		{"no port keeps url", "https://api.openai.com/v1", "https://api.openai.com/v1"},
+		{"query string preserved", "http://10.43.46.12:3000/v1?api-version=2024-05", "http://10.43.46.12/v1?api-version=2024-05"},
+		{"escaped path preserved", "http://10.43.46.12:3000/v1/models%2Ffoo", "http://10.43.46.12/v1/models%2Ffoo"},
+		{"ipv6 port with path", "http://[2001:db8::1]:3000/v1", "http://[2001:db8::1]/v1"},
+		{"ipv6 no port keeps brackets", "http://[2001:db8::1]/v1", "http://[2001:db8::1]/v1"},
+		{"unparseable returns input", "://bad", "://bad"},
+	}
+	for _, tc := range cases {
+		t.Run(tc.name, func(t *testing.T) {
+			if got := customOpenAIURL(tc.in); got != tc.want {
+				t.Fatalf("customOpenAIURL(%q) = %q, want %q", tc.in, got, tc.want)
+			}
+		})
+	}
+}
diff --git a/changelog/current.md b/changelog/current.md
index 8c557fe82..8e87b43b8 100644
--- a/changelog/current.md
+++ b/changelog/current.md
@@ -7,6 +7,7 @@ Record image-affecting changes to `manager/`, `worker/`, `copaw/`, `hermes/`, `o
 **Bug Fixes**
 
 - **CoPaw Team coordination routing**: Route Team Leader worker assignments sent through the `message` tool from Leader DM to Team Room, matching the Matrix channel send path. ([92c8145](https://github.com/agentscope-ai/AgentTeams/commit/92c8145))
+- **openai-compat provider with IP:port base URL**: Strip the port from `openaiCustomUrl` in the controller initializer and `setup-higress.sh`, so Higress derives the host domain without the port. Previously a base URL like `http://10.43.46.12:3000/v1` produced host domain `10.43.46.12:3000`, breaking DNS resolution; the port is now supplied only via `openaiCustomServicePort`. (#1057)
 
 **Branding and Compatibility**
 
diff --git a/manager/scripts/init/setup-higress.sh b/manager/scripts/init/setup-higress.sh
index 3447d397b..07858a260 100755
--- a/manager/scripts/init/setup-higress.sh
+++ b/manager/scripts/init/setup-higress.sh
@@ -209,6 +209,15 @@ if [ -n "${AGENTTEAMS_LLM_API_KEY}" ]; then
                 OC_DOMAIN="${OC_URL_STRIP%%/*}"
                 echo "${OC_DOMAIN}" | grep -q ':' && { OC_PORT="${OC_DOMAIN##*:}"; OC_DOMAIN="${OC_DOMAIN%:*}"; }
 
+                # Build openaiCustomUrl WITHOUT the port: Higress derives the
+                # host domain from this URL, so an embedded port would break
+                # DNS resolution. The port is supplied via openaiCustomServicePort.
+                OC_PATH=""
+                case "${OC_URL_STRIP}" in
+                    */*) OC_PATH="/${OC_URL_STRIP#*/}" ;;
+                esac
+                OC_CUSTOM_URL="${OC_PROTO}://${OC_DOMAIN}${OC_PATH}"
+
                 # Service source: GET → PUT if exists, POST if not
                 existing_svc=$(higress_get /v1/service-sources/openai-compat)
                 SVC_BODY='{"type":"dns","name":"openai-compat","port":'"${OC_PORT}"',"protocol":"'"${OC_PROTO}"'","proxyName":"","domain":"'"${OC_DOMAIN}"'"}'
@@ -218,7 +227,7 @@ if [ -n "${AGENTTEAMS_LLM_API_KEY}" ]; then
                     higress_api POST /v1/service-sources "Registering openai-compat DNS service source" "${SVC_BODY}"
                 fi
 
-                PROVIDER_BODY='{"type":"openai","name":"openai-compat","tokens":["'"${AGENTTEAMS_LLM_API_KEY}"'"],"version":0,"protocol":"openai/v1","tokenFailoverConfig":{"enabled":false},"rawConfigs":{"openaiCustomUrl":"'"${OPENAI_BASE_URL}"'","openaiCustomServiceName":"openai-compat.dns","openaiCustomServicePort":'"${OC_PORT}"',"hiclawMode":true}}'
+                PROVIDER_BODY='{"type":"openai","name":"openai-compat","tokens":["'"${AGENTTEAMS_LLM_API_KEY}"'"],"version":0,"protocol":"openai/v1","tokenFailoverConfig":{"enabled":false},"rawConfigs":{"openaiCustomUrl":"'"${OC_CUSTOM_URL}"'","openaiCustomServiceName":"openai-compat.dns","openaiCustomServicePort":'"${OC_PORT}"',"hiclawMode":true}}'
                 existing_provider=$(higress_get /v1/ai/providers/openai-compat)
                 if [ -n "${existing_provider}" ]; then
                     higress_api PUT /v1/ai/providers/openai-compat "Updating LLM provider (openai-compat)" "${PROVIDER_BODY}"