diff --git a/src/wp-includes/block-supports/elements.php b/src/wp-includes/block-supports/elements.php
index 54b96aa1dc064..d765a2c2b4b5a 100644
--- a/src/wp-includes/block-supports/elements.php
+++ b/src/wp-includes/block-supports/elements.php
@@ -12,11 +12,10 @@
  * @since 6.0.0
  * @access private
  *
- * @param array $block Block object.
  * @return string The unique class name.
  */
-function wp_get_elements_class_name( $block ) {
-	return 'wp-elements-' . md5( serialize( $block ) );
+function wp_get_elements_class_name(): string {
+	return wp_unique_prefixed_id( 'wp-elements-' );
 }
 
 /**
@@ -109,6 +108,29 @@ function wp_should_add_elements_class_name( $block, $options ) {
  *
  * @param array $parsed_block The parsed block.
  * @return array The same parsed block with elements classname added if appropriate.
+ *
+ * @phpstan-param array{
+ *     blockName: string,
+ *     attrs: array{
+ *         className?: string,
+ *         style?: array{
+ *             elements?: array<string, array{
+ *                 ":hover"?: array<string, string>,
+ *                 ...
+ *             }>,
+ *         },
+ *         ...
+ *     },
+ *     ...
+ * } $parsed_block
+ * @phpstan-return array{
+ *     blockName: string,
+ *     attrs: array{
+ *         className?: string,
+ *         ...
+ *     },
+ *     ...
+ * }
  */
 function wp_render_elements_support_styles( $parsed_block ) {
 	/*
@@ -129,9 +151,12 @@ function wp_render_elements_support_styles( $parsed_block ) {
 		);
 	}
 
-	$block_type           = WP_Block_Type_Registry::get_instance()->get_registered( $parsed_block['blockName'] );
-	$element_block_styles = $parsed_block['attrs']['style']['elements'] ?? null;
+	$block_type = WP_Block_Type_Registry::get_instance()->get_registered( $parsed_block['blockName'] );
+	if ( ! $block_type ) {
+		return $parsed_block;
+	}
 
+	$element_block_styles = $parsed_block['attrs']['style']['elements'] ?? null;
 	if ( ! $element_block_styles ) {
 		return $parsed_block;
 	}
@@ -157,7 +182,7 @@ function wp_render_elements_support_styles( $parsed_block ) {
 		return $parsed_block;
 	}
 
-	$class_name         = wp_get_elements_class_name( $parsed_block );
+	$class_name         = wp_get_elements_class_name();
 	$updated_class_name = isset( $parsed_block['attrs']['className'] ) ? $parsed_block['attrs']['className'] . " $class_name" : $class_name;
 
 	_wp_array_set( $parsed_block, array( 'attrs', 'className' ), $updated_class_name );
@@ -197,7 +222,7 @@ function wp_render_elements_support_styles( $parsed_block ) {
 				)
 			);
 
-			if ( isset( $element_style_object[':hover'] ) ) {
+			if ( isset( $element_style_object[':hover'], $element_config['hover_selector'] ) ) {
 				wp_style_engine_get_styles(
 					$element_style_object[':hover'],
 					array(
diff --git a/tests/phpunit/tests/block-supports/wpRenderElementsSupport.php b/tests/phpunit/tests/block-supports/wpRenderElementsSupport.php
index 007ba8312e495..ad60844813188 100644
--- a/tests/phpunit/tests/block-supports/wpRenderElementsSupport.php
+++ b/tests/phpunit/tests/block-supports/wpRenderElementsSupport.php
@@ -159,6 +159,70 @@ public function test_elements_block_support_class_with_invalid_elements_prefix()
 		);
 	}
 
+	/**
+	 * Tests that duplicate blocks get distinct elements class names
+	 * on their rendered markup to avoid CSS cascade conflicts.
+	 *
+	 * @ticket 65435
+	 *
+	 * @covers ::wp_get_elements_class_name
+	 */
+	public function test_elements_block_support_class_with_duplicate_blocks(): void {
+		$this->test_block_name = 'test/element-block-supports';
+
+		register_block_type(
+			$this->test_block_name,
+			array(
+				'api_version' => 3,
+				'attributes'  => array(
+					'style' => array(
+						'type' => 'object',
+					),
+				),
+				'supports'    => array(
+					'color' => array(
+						'link' => true,
+					),
+				),
+			)
+		);
+
+		$block = array(
+			'blockName' => $this->test_block_name,
+			'attrs'     => array(
+				'style' => array(
+					'elements' => array(
+						'link' => array(
+							'color' => array(
+								'text' => 'var:preset|color|vivid-red',
+							),
+						),
+					),
+				),
+			),
+		);
+
+		$block_markup         = '<p>Hello <a href="http://www.wordpress.org/">WordPress</a>!</p>';
+		$elements_class_names = array();
+		$count                = 2;
+		for ( $i = 0; $i < $count; $i++ ) {
+			$rendered_block = wp_render_elements_class_name( $block_markup, wp_render_elements_support_styles( $block ) );
+
+			$processor = new WP_HTML_Tag_Processor( $rendered_block );
+			$this->assertTrue( $processor->next_tag( 'P' ), "Expected paragraph in block #$i." );
+			$elements_class_name = array_first(
+				array_filter(
+					iterator_to_array( $processor->class_list() ),
+					fn( string $class_name ) => (bool) preg_match( '/^wp-elements-\d+$/', $class_name )
+				)
+			);
+			$this->assertIsString( $elements_class_name, "Expected wp-elements class in block #$i." );
+			$elements_class_names[] = $elements_class_name;
+		}
+
+		$this->assertSame( $count, count( array_unique( $elements_class_names ) ), 'Expected each rendered block to have a unique wp-elements class name.' );
+	}
+
 	/**
 	 * Data provider.
 	 *
@@ -238,7 +302,7 @@ public function data_elements_block_support_class() {
 					'button' => array( 'color' => $color_styles ),
 				),
 				'block_markup'    => '<p>Hello <a href="http://www.wordpress.org/">WordPress</a>!</p>',
-				'expected_markup' => '/^<p class="wp-elements-[a-f0-9]{32}">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
+				'expected_markup' => '/^<p class="wp-elements-\d+">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
 			),
 			'link element styles apply class to wrapper'   => array(
 				'color_settings'  => array( 'link' => true ),
@@ -246,7 +310,7 @@ public function data_elements_block_support_class() {
 					'link' => array( 'color' => $color_styles ),
 				),
 				'block_markup'    => '<p>Hello <a href="http://www.wordpress.org/">WordPress</a>!</p>',
-				'expected_markup' => '/^<p class="wp-elements-[a-f0-9]{32}">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
+				'expected_markup' => '/^<p class="wp-elements-\d+">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
 			),
 			'heading element styles apply class to wrapper' => array(
 				'color_settings'  => array( 'heading' => true ),
@@ -254,7 +318,7 @@ public function data_elements_block_support_class() {
 					'heading' => array( 'color' => $color_styles ),
 				),
 				'block_markup'    => '<p>Hello <a href="http://www.wordpress.org/">WordPress</a>!</p>',
-				'expected_markup' => '/^<p class="wp-elements-[a-f0-9]{32}">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
+				'expected_markup' => '/^<p class="wp-elements-\d+">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
 			),
 			'element styles apply class to wrapper when it has other classes' => array(
 				'color_settings'  => array( 'link' => true ),
@@ -262,7 +326,7 @@ public function data_elements_block_support_class() {
 					'link' => array( 'color' => $color_styles ),
 				),
 				'block_markup'    => '<p class="has-dark-gray-background-color has-background">Hello <a href="http://www.wordpress.org/">WordPress</a>!</p>',
-				'expected_markup' => '/^<p class="has-dark-gray-background-color has-background wp-elements-[a-f0-9]{32}">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
+				'expected_markup' => '/^<p class="has-dark-gray-background-color has-background wp-elements-\d+">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
 			),
 			'element styles apply class to wrapper when it has other attributes' => array(
 				'color_settings'  => array( 'link' => true ),
@@ -270,7 +334,7 @@ public function data_elements_block_support_class() {
 					'link' => array( 'color' => $color_styles ),
 				),
 				'block_markup'    => '<p id="anchor">Hello <a href="http://www.wordpress.org/">WordPress</a>!</p>',
-				'expected_markup' => '/^<p class="wp-elements-[a-f0-9]{32}" id="anchor">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
+				'expected_markup' => '/^<p class="wp-elements-\d+" id="anchor">Hello <a href="http:\/\/www.wordpress.org\/">WordPress<\/a>!<\/p>$/',
 			),
 		);
 	}
diff --git a/tests/phpunit/tests/block-supports/wpRenderElementsSupportStyles.php b/tests/phpunit/tests/block-supports/wpRenderElementsSupportStyles.php
index 16ed26fc9c7bc..5c9fc8af5819d 100644
--- a/tests/phpunit/tests/block-supports/wpRenderElementsSupportStyles.php
+++ b/tests/phpunit/tests/block-supports/wpRenderElementsSupportStyles.php
@@ -68,6 +68,62 @@ public function test_elements_block_support_styles( $color_settings, $elements_s
 		);
 	}
 
+	/**
+	 * Tests that identical blocks with different elements styles
+	 * generate distinct class names to avoid CSS cascade conflicts.
+	 *
+	 * @ticket 65435
+	 *
+	 * @covers ::wp_get_elements_class_name
+	 */
+	public function test_elements_block_support_styles_with_duplicate_blocks(): void {
+		$this->test_block_name = 'test/element-block-supports';
+
+		register_block_type(
+			$this->test_block_name,
+			array(
+				'api_version' => 3,
+				'attributes'  => array(
+					'style' => array(
+						'type' => 'object',
+					),
+				),
+				'supports'    => array(
+					'color' => array(
+						'link' => true,
+					),
+				),
+			)
+		);
+
+		$block = array(
+			'blockName' => $this->test_block_name,
+			'attrs'     => array(
+				'style' => array(
+					'elements' => array(
+						'link' => array(
+							'color' => array(
+								'text' => 'blue',
+							),
+						),
+					),
+				),
+			),
+		);
+
+		// Process two identical blocks with the same elements styles.
+		$count = 2;
+		for ( $i = 0; $i < $count; $i++ ) {
+			wp_render_elements_support_styles( $block );
+		}
+		$actual_stylesheet = wp_style_engine_get_stylesheet_from_context( 'block-supports', array( 'prettify' => false ) );
+
+		// Count the number of distinct class names to confirm uniqueness.
+		$this->assertSame( $count, preg_match_all( '/\.wp-elements-(\d+)/', $actual_stylesheet, $matches ) );
+		$unique_classes = array_unique( $matches[1] );
+		$this->assertCount( $count, $unique_classes, 'Both blocks should produce distinct class names' );
+	}
+
 	/**
 	 * Data provider.
 	 *
@@ -127,7 +183,7 @@ public function data_elements_block_support_styles() {
 				'elements_styles' => array(
 					'button' => array( 'color' => $color_styles ),
 				),
-				'expected_styles' => '/^.wp-elements-[a-f0-9]{32} .wp-element-button, .wp-elements-[a-f0-9]{32} .wp-block-button__link' . $color_css_rules . '$/',
+				'expected_styles' => '/^.wp-elements-\d+ .wp-element-button, .wp-elements-\d+ .wp-block-button__link' . $color_css_rules . '$/',
 			),
 			'link element styles are applied'            => array(
 				'color_settings'  => array( 'link' => true ),
@@ -139,15 +195,15 @@ public function data_elements_block_support_styles() {
 						),
 					),
 				),
-				'expected_styles' => '/^.wp-elements-[a-f0-9]{32} a:where\(:not\(.wp-element-button\)\)' . $color_css_rules .
-					'.wp-elements-[a-f0-9]{32} a:where\(:not\(.wp-element-button\)\):hover' . $color_css_rules . '$/',
+				'expected_styles' => '/^.wp-elements-\d+ a:where\(:not\(.wp-element-button\)\)' . $color_css_rules .
+					'.wp-elements-\d+ a:where\(:not\(.wp-element-button\)\):hover' . $color_css_rules . '$/',
 			),
 			'generic heading element styles are applied' => array(
 				'color_settings'  => array( 'heading' => true ),
 				'elements_styles' => array(
 					'heading' => array( 'color' => $color_styles ),
 				),
-				'expected_styles' => '/^.wp-elements-[a-f0-9]{32} h1, .wp-elements-[a-f0-9]{32} h2, .wp-elements-[a-f0-9]{32} h3, .wp-elements-[a-f0-9]{32} h4, .wp-elements-[a-f0-9]{32} h5, .wp-elements-[a-f0-9]{32} h6' . $color_css_rules . '$/',
+				'expected_styles' => '/^.wp-elements-\d+ h1, .wp-elements-\d+ h2, .wp-elements-\d+ h3, .wp-elements-\d+ h4, .wp-elements-\d+ h5, .wp-elements-\d+ h6' . $color_css_rules . '$/',
 			),
 			'individual heading element styles are applied' => array(
 				'color_settings'  => array( 'heading' => true ),
@@ -159,12 +215,12 @@ public function data_elements_block_support_styles() {
 					'h5' => array( 'color' => $color_styles ),
 					'h6' => array( 'color' => $color_styles ),
 				),
-				'expected_styles' => '/^.wp-elements-[a-f0-9]{32} h1' . $color_css_rules .
-					'.wp-elements-[a-f0-9]{32} h2' . $color_css_rules .
-					'.wp-elements-[a-f0-9]{32} h3' . $color_css_rules .
-					'.wp-elements-[a-f0-9]{32} h4' . $color_css_rules .
-					'.wp-elements-[a-f0-9]{32} h5' . $color_css_rules .
-					'.wp-elements-[a-f0-9]{32} h6' . $color_css_rules . '$/',
+				'expected_styles' => '/^.wp-elements-\d+ h1' . $color_css_rules .
+					'.wp-elements-\d+ h2' . $color_css_rules .
+					'.wp-elements-\d+ h3' . $color_css_rules .
+					'.wp-elements-\d+ h4' . $color_css_rules .
+					'.wp-elements-\d+ h5' . $color_css_rules .
+					'.wp-elements-\d+ h6' . $color_css_rules . '$/',
 			),
 		);
 	}