DESCRIPTION

Package: TissueField
Title: Steady-State Molecular Concentration Fields for Spatial Transcriptomics
Version: 0.1.0
Authors@R: person("Raredon Laboratory", role = c("aut", "cre"),
    email = "raredon@yale.edu")
Description: Computes continuous steady-state molecular concentration fields
    from discrete mRNA transcript or protein detection coordinates, using a
    physically motivated diffusion-clearance model. Solves the screened
    Poisson PDE (D * nabla^2 C - lambda * C + s = 0) via one of three
    methods: finite-difference sparse linear system, Green's function FFT
    convolution, or Gaussian kernel density estimation. Designed for use
    with spatial transcriptomics and spatial proteomics data. Works
    naturally with tissue masks produced by the TissueMask package.
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Depends: R (>= 4.1.0)
Imports:
    sf (>= 1.0-0),
    Matrix (>= 1.3-0),
    stats,
    parallel
Suggests:
    ggplot2,
    patchwork,
    testthat (>= 3.0.0),
    knitr,
    rmarkdown,
    TissueMask
Config/testthat/edition: 3
VignetteBuilder: knitr
URL: https://github.com/RaredonLab/TissueField
BugReports: https://github.com/RaredonLab/TissueField/issues