diff --git a/setup.py b/setup.py
index fb60abc..e11195d 100644
--- a/setup.py
+++ b/setup.py
@@ -40,7 +40,7 @@
         "mrcfile",
         "pandas",
         "fair-esm==1.0.3",
-        "pyhmmer==0.7.1",
+        "pyhmmer>=0.11.0",
         "loguru",
         "numpy<2.0",
     ],